Lamivudine (Epivir HBV)

Other Names: 3TC

All Clinical Trials

BEHoLD: HBeAg-Negative Industry

Official Title A Phase III Study of Entecavir vs Lamivudine in Adults With Chronic Hepatitis B Infection and Negative for Hepatitis B e Antigen

Phase Phase III

ClinicalTrials.gov NCT00035789

Treatments

Entecavir

Tradename:BaracludeOther Names:ETVClass:Oral Antivirals (Nucleos(t)ide Analogues)

Lamivudine

Tradename:Epivir HBVOther Names:3TCClass:Oral Antivirals (Nucleos(t)ide Analogues)

Funding

IndustryBristol-Meyers Squibb

References

Lai CL, Shouval D, Lok AS, et al. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med. 2006;354:1011-20.
[PubMed Abstract]

BEHoLD: HBeAg-Positive Industry

Official Title A Phase III Study of Entecavir vs Lamivudine in Adults With Chronic Hepatitis B Infection and Positive for Hepatitis B E Antigen

Phase Phase III

ClinicalTrials.gov NCT00035633

Treatments

Entecavir

Tradename:BaracludeOther Names:ETVClass:Oral Antivirals (Nucleos(t)ide Analogues)

Lamivudine

Tradename:Epivir HBVOther Names:3TCClass:Oral Antivirals (Nucleos(t)ide Analogues)

Funding

IndustryBristol-Meyers Squibb

References

Chang TT, Gish RG, de Man R, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med. 2006;354:1001-10.
[PubMed Abstract]
Gish RG, Lok AS, Chang TT, et al. Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B. Gastroenterology. 2007;133:1437-44.
[PubMed Abstract]

Globe Industry

Official Title A Randomized, Double Blind Trial of LdT (Telbivudine) Versus Lamivudine in Adults With Compensated Chronic Hepatitis B

Phase Phase III

ClinicalTrials.gov NCT00057265

Treatments

Lamivudine

Tradename:Epivir HBVOther Names:3TCClass:Oral Antivirals (Nucleos(t)ide Analogues)

Funding

IndustryNovartis

References

Lai CL, Gane E, Liaw YF, et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med. 2007;357:2576-88.
[PubMed Abstract]

Peginterferon alfa-2a HBeAg-Negative Study Group Industry

Official Title Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis

Treatments

Lamivudine

Tradename:Epivir HBVOther Names:3TCClass:Oral Antivirals (Nucleos(t)ide Analogues)

Peginterferon alfa-2a

Tradename:PegasysClass:Immune Modulators (Interferons)

Funding

IndustryRoche

References

Marcellin P, Bonino F, Lau GK, et al. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a. Gastroenterology. 2009;136:2169-79.
[PubMed Abstract]
Marcellin P, Lau GK, Bonino F, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med. 2004;351:1206-17.
[PubMed Abstract]

Peginterferon alfa-2a HBeAg-Positive Study Group Industry

Official Title Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B

Phase Phase III

Treatments

Lamivudine

Tradename:Epivir HBVOther Names:3TCClass:Oral Antivirals (Nucleos(t)ide Analogues)

Peginterferon alfa-2a

Tradename:PegasysClass:Immune Modulators (Interferons)

Funding

IndustryRoche

References

Lau GK, Piratvisuth T, Luo KX, et al. Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Engl J Med. 2005;352:2682-95.
[PubMed Abstract]

Lamivudine Slide Deck

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March 3, 2020

Clinical Trial Image Decks

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BEHoLD: HBeAg-Negative - February 24, 2020

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BEHoLD: HBeAg-Positive - March 3, 2020

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Globe - February 24, 2020

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Peginterferon alfa-2a HBeAg-Negative Study Group - February 24, 2020

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Peginterferon alfa-2a HBeAg-Positive Study Group - February 24, 2020

Topics

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Topics

Oral Antivirals (Nucleos(t)ide Analogues)

Immune Modulators (Interferons)

Vaccines (HBV)

Lamivudine (Epivir HBV)

All Clinical Trials

Entecavir

Lamivudine

Entecavir

Lamivudine

Lamivudine

Lamivudine

Peginterferon alfa-2a

Lamivudine

Peginterferon alfa-2a

Lamivudine Slide Deck

Clinical Trial Image Decks

Topics

Topics

Topics

Topics

Topics

Topics

Topics

Topics

Topics

Topics

Topics

Oral Antivirals (Nucleos(t)ide Analogues)

Immune Modulators (Interferons)

Vaccines (HBV)

Lamivudine (Epivir HBV)

All Clinical Trials

Entecavir

Lamivudine

Entecavir

Lamivudine

Lamivudine

Lamivudine

Peginterferon alfa-2a

Lamivudine

Peginterferon alfa-2a

Lamivudine Slide Deck

Clinical Trial Image Decks

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